News

Kedia and colleagues found the Serpina3n oligodendrocytes had swelled with myelin basic protein (MBP), and their processes had fragmented, suggesting they were overwhelmed with myelin. Scanning ...
During this time he determined the influence of novel myelin proteins on the regulation of voltage-gated calcium channels in developing oligodendrocytes, and investigated the expression of the myelin ...
In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin.
Here, we report that RNA-level expression of RNLTR12-int, a retrotransposon of retroviral origin, is essential for myelination. We show that RNLTR12-int-encoded RNA binds to the transcription factor ...
They insulated axons of all diameters in the white matter; myelin basic protein levels seemed normal. Even so, on closer inspection, McNamara found that all was not well with the myelin around FIREΔ/Δ ...
In addition, immunostaining analyses for the myelin basic protein (MBP), oligodendrocyte progenitor cells (OPCs), and anti-Olig2 were performed.
Using this strategy, blood‐born cells engineered to overexpress the missing brain protein were reported to infiltrate the brain, which raised parenchymal levels of the protein in question and ...
Comparison with previously established mRNA-abundance profiles shows that expression of many myelin-related transcripts coincides with the maturation of zebrafish oligodendrocytes. Zebrafish myelin ...