The myelin sheath of nerve fibers was first discovered and described by Rudolf Virchow in 1854. Myelin is composed of about 40% water and the dry mass is composed of about 80% lipids and 20% protein.

Zasadzinski, Husted and Israelachvili also discovered that the myelin basic protein acts as a patch to fill in any holes in the myelin bilayers. "It is similar to the stuff you put in your tires ...

New research published in The FEBS Journal reveals the importance of a protein called ... C1QL1 protein identified as key to myelin replacement. 1mo. ... Our basic research on C1QL1 is nascent, ...

For this aim an assay was performed with the full length GST-VRK1 protein using as substrates, casein, phosvitin, histone 2b, histone 3, and myelin basic protein (MBP). The results are shown in ...

The findings are not only relevant to basic research, but also to medicine. Targeted stimulation of Nfat proteins could perhaps be used in the future to promote the formation of new myelin sheaths ...

The RNA/protein combination binds to DNA near the gene for myelin basic protein, or MBP, a major component of myelin. “MBP is essential for the membrane growth and compression of ...

Phosphorylation of Pmk1 was examined using anti-phospho Pmk1 antibodies. b, ... and GST–Rnc1 purified from fission yeast in place of the myelin basic protein was used as a substrate. ...

Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.

The neurons of the brain are protected by an insulating layer called myelin. ... C1QL1 protein identified as key to myelin replacement. Download PDF Copy; ... Our basic research on C1QL1 is ...

Regenerating Myelin In The Brain Could Be ... observed that a protein called Daam2 can stop oligodendrocytes from ... a form of Daam2 that had been altered by phosphorylation, ...

Using biochemical approaches, they found two amino acid residues (Ser704 and Thr705) of Daam2 protein undergo phosphorylation - a common post-translational regulatory mechanism that turns on or ...

Myelin sheath protein changes linked to impaired nerve signaling in Alzheimer's disease. Story by Isabella Backman • 8m. T he disruption of axons—the thread-like part of nerve cells that ...