Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for ...

Objectives: It has been suggested that autoimmunity to peripheral myelin proteins is involved in the pathogenesis of Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating ...

New research published in The FEBS Journal reveals the importance of a protein called C1QL1 for promoting the replacement of the specialized cells that produce myelin.

Kedia and colleagues found the Serpina3n oligodendrocytes had swelled with myelin basic protein (MBP), and their processes had fragmented, suggesting they were overwhelmed with myelin. Scanning ...

A retrovirus embedded in the DNA of some vertebrates helps turn on production of a protein needed to insulate nerve cells, aiding speedy thoughts.

Ancient retroviruses played a key role in the evolution of vertebrate brains Date: February 15, 2024 Source: Cell Press Summary: Researchers report that ancient viruses may be to thank for myelin ...

In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin. When they experimentally inhibited ...

After all, these specialized cells wrap cholesterol-laden myelin around axons in the brain's white matter beginning early in development, and throughout life they sustain and repair this insulation.

In addition, immunostaining analyses for the myelin basic protein (MBP), oligodendrocyte progenitor cells (OPCs), and anti-Olig2 were performed.

In this review, we focus on aspects of myelin composition that are peculiar to this structure and differentiate it from the more conventional cell membranes, with special attention to its constituent ...

The sacs of cellular content released by myelin-producing cells of the brain and spinal cord may be potential diagnostic biomarkers for MS, a study has found.