One CNS autoimmune disease that causes multifocal inflammation, mostly in the optic nerves and spinal cord, is NMOSD. The median age at onset is 40 years, with 20% of patients being children or adults ...

Dose constraints to other OARs (such as the optic chiasm and brainstem) were prescribed as clinically indicated and prioritized over hippocampal constraints. The evaluation of the treatment plans was ...