Dr. Frank Brodkey shares key insights from andexanet's development, approval, and real-world clinical trajectory.
Trauma care has long been characterised by empiric, protocol-driven interventions. While these approaches provide a broad framework, there is a growing recognition that treatment should be tailored to ...
Background: Coagulopathy after cardiac surgery is a major cause of morbidity and mortality. While prothrombin complex concentrate (PCC) is increasingly used as an alternative to fresh frozen plasma ...
Background: Fresh frozen plasma (FFP) is conventionally used for the management of bleeding and reversal of coagulopathy in cardiac surgery. It carries the risk of complications like volume overload ...
TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech ...
Royal Columbian Hospital is one of 12 North American hospitals involved in a study that has been published in the Journal of the American Medical Association (JAMA). Even though blood is red, the main ...
For patients who experience excessive bleeding during cardiac surgery, four-factor prothrombin complex concentrate (4F-PCC), a blood product that contains clotting factors, is significantly more ...
A new international study has found that prothrombin complex concentrate (PCC) is not only safer but also more effective than frozen plasma in treating excessive bleeding caused by coagulation factor ...
The following is a summary of “Reversal of Factor Xa Inhibitor-Related Intracranial Hemorrhage: A Multicenter, Retrospective, Observational Study Comparing the Efficacy and Safety of Andexanet and ...