Since then, biochemistry, electron microscopy and electrophysiology have unravelled the crucial role of the sarcoplasmic reticulum in the control of muscle contraction.

Calcium-uptake and ATPase studies carried out on fragmented sarcoplasmic reticulum from muscle of patients with Duchenne dystrophy showed low initial and total calcium uptake, low ATPase activity a ...

A new method for assessing sarcoplasmic reticulum (SR) Ca2+-leak in atrial myocytes using confocal line-scan Ca2+ imaging is proposed. This approach offers a simpler and more ...

Sarcoplasmic reticulum/endoplasmic reticulum ATPase 2a (SERCA2a) is a calcium pump for calcium ion recycling in the sarcoplasmic reticulum in cardiomyocytes.

Muscle contraction is known to be regulated by calcium. An action potential generated by a motor neuron propagates on the muscle cell surface, activates voltage-gated calcium channels and allows ...