An interaction between two proteins points to a molecular basis for memory. But how do memories last when the molecules that ...

Imagine the magnificent glaciers of Greenland, the eternal snow of the Tibetan high mountains, and the permanently ice-cold ...

Rational drug design depends on the knowledge of the three-dimensional (3D) structure of complexes between proteins and lead compounds of low molecular weight. A novel nuclear magnetic resonance (NMR) ...

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying ...

New research reveals that Alzheimer's disease may impair nerve function not by reducing myelin, but by altering the proteins ...

Expression of the differentiation inhibitors ID2 and ID4 was enhanced, whereas expression of myelin proteins such as myelin basic protein (MBP) and 2′,3′-cyclic nucleotide phosphodiesterase ...

As time goes by, our bodies change, you know, even the brain. A major change is how brain structure seems to shrink with age. Studies show that this happens at both large and small levels inside. You ...

Download figure Open in new tab Download powerpoint Figure 1 (A) Myelin basic protein (MBP) levels in the cerebrospinal fluid (CSF) of the anti-aquaporin-4 (AQP4-Ab)-positive, anti-myelin ...

To better understand any pathological processes related to Alzheimer's disease that might affect the myelin sheath, Yale researchers analyzed proteins in human brain tissue, focusing on the sub ...

When the structure is impaired, so is the conduction of electrical signals. To better understand any pathological processes related to Alzheimer’s disease that might affect the myelin sheath, Yale ...

Machine learning methods are widely used in bioinformatics and computational and systems biology. Here, we review the development of machine learning methods for protein structure prediction, one of ...