Lipid domains control myelin basic protein adsorption and membrane interactions between model myelin lipid bilayers. Proceedings of the National Academy of Sciences , 2014; 111 (8): E768 DOI: 10. ...

Myelin segments are stained in red by an antibody to myelin basic protein, a molecule specifically expressed in myelin. Nodes of Ranvier (arrows) are stained in green by an antibody to nodal ...

The disruption of axons—the thread-like part of nerve cells that transmits electrical signals—is associated with Alzheimer's disease. One way axonal function may be hindered is through damage to the ...

The current study analyzed the synthesis of myelin basic protein (MBP), a substance which is essential for the formation and stabilization of myelin membranes. In common with all proteins, MBP is ...

Targeted stimulation of Nfat proteins could perhaps be used in the future to promote the formation of new myelin sheaths in MS patients, for example after a relapse. However, such stimulating ...

The 2023 Lasker Award for Basic Medical Research underscores the value of an AI system that predicts the three-dimensional structure of proteins from the one-dimensional sequence of their amino acids.

DeepMind says its AlphaFold tool has successfully predicted the structure of nearly all proteins known to science. The AI lab is offering its database of over 200 million proteins to anyone for free.

Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.

"In contrast with unaffected areas of the brain in which the myelin structure appears normal, ... Myelin Basic Protein synthesis is regulated by small non-coding RNA 715. EMBO reports, 2012; 13 ...