Loss or inhibition of phosphodiesterase 4D enzymatic activity leads to calcium leak, heart failure and arrhythmia. ... the region between the cardiac sarcolemma and sarcoplasmic reticulum (SR).

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy. JCI Insight , 2019; 4 (11) DOI: 10.1172/jci.insight.123855 Cite This Page : ...

Findings on electrocardiography, echocardiography, and cardiac magnetic resonance imaging were normal. ... (MHC) class I antigen on the sarcolemma and sarcoplasm of muscle fibers, ...

A new multi-institution study spearheaded by researchers at Florida State University and the University of California, Los Angeles suggests a tiny protein could play a major role in combating ...