Sarcomere-Mediated Mechanotransduction The sarcomere is the molecular motor of the cardiac myocyte, and forces generated by actin–myosin interactions are transmitted in a complex fashion through the ...

Thomas Mallon’s diaries take us back to the AIDS crisis, the heyday of magazines and an exhilarating city in “The Very Heart of It.” ...

“Cardiac clearance” can reveal heart issues, reduce surgical risk and even save a life. The evaluation helps ensure your body is ready for the stress of an operation.

Loss of dystroglycan function in ventricular cardiac myocytes was not sufficient to cause the early mortality that was observed in myd mice less than 1 year of age. However, at 50 weeks of age mice ...

In the heart, the basement membrane links directly to the cardiac muscle fiber membrane (i.e., sarcolemma) via transmembrane receptors. Cardiac and skeletal muscle cells contain transverse (t)-tubules ...

Kitmitto, A., Baudoin, F. and Cartwright, E.J. (2019) Cardiomyocyte Damage Control in Heart Failure and the Role of the Sarcolemma. Journal of Muscle Research and Cell Motility, 40, 319-333.

Conclusion: Corin deficiency impairs cardiac function and exacerbates HF development in mice. Corin protein may be used to reduce cardiac hypertrophy and fibrosis, suppress the ...

Cardiac cirrhosis or congestive hepatopathy is a term to describe liver disorders that occur due to underlying heart dysfunction. Learn more here.

Dystrophic cardiomyopathy arises from mutations in the dystrophin gene. Dystrophin forms part of the dystrophin glycoprotein complex and is postulated to act as a membrane stabilizer, protecting the ...

Cardiac asthma is a condition caused by heart failure that leads to asthma-like symptoms. Read on to learn everything you need to know about cardiac asthma, including what causes it, its symptoms ...