Here we provide the first evidence that tetraspanin CD151 can support de novo carcinogenesis. During two-stage mouse skin chemical carcinogenesis, CD151 reduces tumor lag time and increases ...

Background: CD151 is a tetraspanin protein linked to cellular growth and motility. Recent work has suggested that CD151 may play a role in metastases in a variety of cancers, but as yet there is no ...

Interrogation of Functional Cell-Surface Markers Identifies CD151 Dependency in High-Grade Serous Ovarian Cancer. Cell Reports, 2017; 18 (10): 2343 DOI: 10.1016/j.celrep.2017.02.028; ...