They examined the sorted subtypes with super-resolution microscopy to find that all subtypes primarily used integrin heterodimers associated with a specific tetraspanin protein known as CD151 and ...

Notably, while CD151 primarily functions as an oncogene in various malignancies, evidence suggests that its role is context-dependent, with tumor-suppressive effects observed in certain cancers. This ...

Distinct from its canonical function in strengthening cell adhesion at cell surface, CD151 maintains endolysosome function by sustaining VCP/p97-mediated protein unfolding and turnover. By supporting ...

CD151 was identified as an ideal TAA based on proteomic and bioinformatic analyses. CD151 peptides as tumour vaccines triggered active anti-tumour immunity against H22 hepatoma and the lung metastasis ...

BACKGROUND: Tetraspanin CD151 is highly expressed in endothelia and reinforces cell adhesion, but its role in vascular inflammation remains largely unknown. METHODS: In vitro molecular and cellular ...

To detect candidate genes for PRRSv resistance, it is essential to have basic knowledge regarding molecules involved in PRRS pathogenesis. Recognition of specific cell receptors – including CD163, ...

The role played by CD151 in HCC has been elucidated in detail from laboratory studies to the effects on clinical prognosis. All these studies suggest that the upregulation of CD151 might be a ...

It demonstrates the EV-Chip’s clinical potential to evaluate human liquid biopsy samples through rapid, label-free identification of known biomarkers, CD63 and CD151.

The Chief Executive Officer is asked to approve: Total expenditure of up to £95,000 in the form of a grant to West London Business Ltd. The grant will be used to pay for the PRBG Manager's salary ...

Here, Cd151-deletion led to an upregulation of ECM- and collagen assembly-associated genes that are linked with disturbances in lung function. Our results, therefore, suggested that Cd151-deletion ...

CD151 has been recognized as a prognostic marker, the therapeutic target of breast cancers, but less explored for small molecule inhibitors due to lack of a validated model. The 3-D structure of CD151 ...