The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

Synaptic transmission is the biological process by which a neuron communicates with a target cell across a synapse. Chemical synaptic transmission involves the release of a neurotransmitter from ...

However, the intricate mechanisms governing these processes have remained elusive due to the presence of multiple functional domains within Munc13, each playing distinct roles in neurotransmitter ...

This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...

If the load of the membrane controlled the rates of endocytosis, exocytosis or of lamellipodial retraction and extension, the cell would 'automatically' adjust the membrane area to compensate for ...