Deleting a gene called PTEN in certain brain cells disrupts the brain’s fear circuitry and triggers anxiety-like behavior in ...

Interneurons work a bit like the brain's traffic controllers where they regulate the firing of other brain cells, acting like ...

Researchers have uncovered how losing the autism-linked gene PTEN in a specific set of inhibitory neurons reshapes brain circuits tied to fear and anxiety.

Research from the Max Planck Florida Institute reveals that loss of the PTEN gene in inhibitory neurons within the amygdala ...

Commissural interneurons: both halves in step Experiments in rodents and cats have demonstrated the importance of commissural connections for coordinated left–right limb movements 81, 82.

Dubai, United Arab Emirates; June , 2025 - A new Mayo Clinic study finds that people with Tourette syndrome have about half as many of a specific typ ...

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a ...

A breakthrough spinal implant restored movement in paralyzed rats using gentle electric pulses—offering new hope for treating spinal cord injuries in humans.

Thus, to target interneurons at postnatal day 10 that do not yet express PV, Pouchelon et al. (2021) crossed Lhx6-Cre mice to SST-Flp mice and injected an AAV encoding a Flp-OFF construct at birth, ...

NRG1, its receptor ErbB4, or specific interneurons are therefore potential therapeutic targets for neurodevelopmental disorders such as schizophrenia and ASD. Therapeutic strategies might involve ...