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Barcelona-based genetic medicines company SpliceBio has raised $135 million in a series B round to back its novel protein-splicing drug delivery system, the biotech announced Wednesday. The money will ...
New research published in The FEBS Journal reveals the importance of a protein called C1QL1 for promoting the replacement of the specialized cells that produce myelin.
Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.
In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin.
In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin.
The two major central nervous system myelin proteins are the proteolipid proteins (PLP/DM20), highly hydrophobic and cholesterol‐interacting proteins with four transmembrane domains, and the myelin ...
They insulated axons of all diameters in the white matter; myelin basic protein levels seemed normal. Even so, on closer inspection, McNamara found that all was not well with the myelin around FIREΔ/Δ ...
In this review, we focus on aspects of myelin composition that are peculiar to this structure and differentiate it from the more conventional cell membranes, with special attention to its constituent ...
The research showed that levels of myelin basic protein (MBP), a key myelin protein, in these extracellular vesicles are significantly higher in MS patients than in healthy people.