Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83–99) represents one candidate antigen; therefore, it ...

3-Hydroxyquinolin-2-Ones Act as Dual Inhibitors of Ferroptosis and Monoamine Oxidase B: Reducing Alzheimer’s Disease-Related Amyloid Precursor Protein and Hyperphosphorylated Tau In Vivo ...

In this image, an axon appears in green, while abnormal protein clumps (amyloid, red) lodge in tiny channels within the myelin sheath. Amyloid aggregates form filament-like strands across the ...

Demonstrates that neuregulin 1 type III isoforms are the crucial isoforms required for survival of SCPs, for axon fasciculation and for motor and sensory neuron survival in peripheral nerves.