Frontiers3y
Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis
We performed (i) quantitative spatial profiling of the mRNA transcript encoding myelin basic protein ... a housekeeping protein (1:10,000; #A2228 Sigma Aldrich)) overnight at 4°C, appropriate horse ...
eLife4y
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells ... In mice, we find that repair cells express reduced c-Jun protein as regenerative support provided by these cells ...
Frontiers7y
Exposure to the Epstein–Barr Viral Antigen Latent Membrane Protein 1 Induces Myelin-Reactive Antibodies In Vivo
Previously, we showed that monoclonal myelin basic protein (MBP)-specific antibodies from MS patients ... Lys-biotin for binding analysis with MBP and LMP1 utilizing ELISA and WB techniques. Data were ...