Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83–99) represents one candidate antigen; therefore, it ...

Expression of the differentiation inhibitors ID2 and ID4 was enhanced, whereas expression of myelin proteins such as myelin basic protein (MBP) and 2′,3′-cyclic nucleotide phosphodiesterase ...

Download figure Open in new tab Download powerpoint Figure 1 (A) Myelin basic protein (MBP) levels in the cerebrospinal fluid (CSF) of the anti-aquaporin-4 (AQP4-Ab)-positive, anti-myelin ...

In this image, an axon appears in green, while abnormal protein clumps (amyloid, red) lodge in tiny channels within the myelin sheath. Amyloid aggregates form filament-like strands across the ...