Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83–99) represents one candidate antigen; therefore, it ...

Multiple sclerosis (MS) is an auto-immune disease which affects the myelin sheath surrounding the axon, causing axonal degeneration and neuronal loss. Details of the pathogenesis of this disease ...

Myelin-reactive T cells from patients with multiple sclerosis exhibit a memory or activated phenotype, whereas these same antigen-specific cells in healthy persons appear to have a naive phenotype ...

Multiple sclerosis affects more than 2 million people worldwide and is currently incurable. A number of interventions to modify the course of multiple sclerosis have been developed that offer new i ...

Reindl, M. et al. Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain 122 ...

Experts aren’t sure what causes multiple sclerosis, but they have identified four primary risk factors that may interact with each other: immune system malfunction, genetics, environmental ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the fatty sheath that covers nerve cells in the brain and spinal cord.

In multiple sclerosis (MS), macrophages and microglia play a dual role that could be used to treat this neurodegenerative disease. These cells promote inflammation that demyelinates neurons but also ...

Myelin sheath, a sleeve that protects a part of your nerve cells, and how it's related to multiple sclerosis. Read to learn more about its functions and how to protect it from damage. Skip to main ...