Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83–99) represents one candidate antigen; therefore, it ...

Multiple sclerosis (MS) is an auto-immune disease which affects the myelin sheath surrounding the axon, causing axonal degeneration and neuronal loss. Details of the pathogenesis of this disease ...

Reindl, M. et al. Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain 122 ...

Myelin-reactive T cells from patients with multiple sclerosis exhibit a memory or activated phenotype, whereas these same antigen-specific cells in healthy persons appear to have a naive phenotype ...

Multiple sclerosis affects more than 2 million people worldwide and is currently incurable. A number of interventions to modify the course of multiple sclerosis have been developed that offer new i ...

Experts aren’t sure what causes multiple sclerosis, but they have identified four primary risk factors that may interact with each other: immune system malfunction, genetics, environmental ...

In multiple sclerosis (MS), macrophages and microglia play a dual role that could be used to treat this neurodegenerative disease. These cells promote inflammation that demyelinates neurons but also ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the fatty sheath that covers nerve cells in the brain and spinal cord.

Myelin sheath, a sleeve that protects a part of your nerve cells, and how it's related to multiple sclerosis. Read to learn more about its functions and how to protect it from damage. Skip to main ...