In conclusion, thin myofilament regulation clearly can affect force development. Although differences in experimental findings have been reported by investigators who used agents targeted at ...

Evidence from cell culture and animal models indicates that HSP27 and αB-crystallin (cryAB) are dramatically regulated via phosphorylation in response to ischemic insults. The phosphorylation of these ...

The calcium-dependent interactions between troponin C (TnC) and other thin and thick filament proteins play a key role in the regulation of cardiac muscle contraction. Five hydrophobic residues (Phe20 ...