A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or ...

Huntington's Disease Gene Also Enhances Early Brain Development ... potential cause of the genetic mutations that result in rare neurodegenerative ... Drug Significantly Reduces Chorea Symptoms ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

Your genes play a huge role in what makes and shapes your entire existence. Since you inherit your genes from your parents, ...

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The size of the reduction was also dose-dependent. Huntington’s disease is a rare, devastating neurodegenerative genetic disorder that affects motor function and causes severe cognitive decline ...

Using RNA to interfere with a gene’s expression of disease-causing proteins is a validated therapeutic approach, but so far, the products in this drug class only address liver proteins.

Less than a month after researchers unveiled that a “ticking DNA clock” is behind Huntington’s disease (HD), scientists have now identified an antisense oligonucleotide (ASO) that can slow ...

Study uncovers how gradual CAG repeat expansion in neurons drives the onset of Huntington’s disease, offering new insights for potential therapeutic interventions. Study: Long somatic DNA-repeat ...

BOSTON — Scientists are unraveling the mystery of what triggers Huntington's disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts ...

The team found that although functions such as movement, thinking or behaviour remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain ...