250+ Clinical Trials: Hosted at Alpha Clinics for CIRM funded and other research. 2000+ Patients Enrolled: Pioneers who participated in a clinical trial at an Alpha Clinic. 40+ Diseases & Conditions: ...

The California Cell and Gene Therapy Manufacturing Network was established by CIRM to expand the manufacturing capabilities necessary to bring stem cell and gene therapies from foundational research ...

CIRM is supporting a network of 11 Shared Resources Laboratories (SRLs) for Stem Cell-Based Modeling, an important component of CIRM’s Infrastructure Program designed to address challenges that hinder ...

CIRM Disclaimer: The information in the table has been collected by CIRM to help CIRM awardees accelerate the development of pluripotent stem cell-derived therapeutics. The information is intended to ...

下丘脑腹内侧区 (VMHVL) 的雌激素受体 α (ERα) 神经元控制一系列性别特异性反应，以最大限度地提高生殖成功率。 在女性中，这些 VMHVL 神经元被认为负责协调新陈代谢和生殖。 然而，目前尚不清楚特定的神经元群是否控制这种生理功能的不同组成部分。 在这里，我们确定了 ERα VMHVL 神经元的一个 ...

惊悉火箭制药公司（Rocket Pharmaceuticals）RP-A2二期临床试验（用于治疗达农病）的一名受试者不幸去世，我们深感悲痛。加州再生医学研究所（CIRM）为该临床试验提供部分资金，我谨代表该研究所，向患者的家人、挚爱亲朋以及在这段艰难时期悉心照料他们的医疗团队致以最深切的慰问。 达农病是一 ...

Clinical Trial Stage Projects Henry John Klassen A Phase 2 Study of the Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects with Retinitis Pigmentosa $5 ...

Quest – Discovery Stage Research Projects University of California, Berkeley Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury $1,627,099 Tools and ...

我们正在继续努力进行体细胞核移植，以获得免疫相容的胚胎干细胞，用于未来患者的再生医学应用。 由于人类卵母细胞的可用性有限，我们从卵巢肿瘤患者那里获得了人类卵巢皮质碎片，并设计了体外激活方案以促进休眠卵泡的生长，然后移植到免疫缺陷小鼠体内以获得成熟的卵母细胞。 我们 ...

该项目增强了干细胞的可及性、可扩展性和协作性。它提供了特征化的 hPSC 系、CRISPR 编辑和自动化平台上的分化，从而加速了生物学、疾病研究和再生医学的进展。… 继续阅读 干细胞建模的模块化自动化方法可提高通量、再现性和可及性 ...

Traumatic brain injuries (TBI) are the seventh leading cause of disability globally with 48.99 million prevalent cases and 7.08 million years lived with diability. Approximately 80 % of TBI patients ...

Trophoblast stem cells (TSCs) are crucial for developing the placenta, as they can produce all the cell types needed for its function. Culturing TSCs in the lab provides a valuable model to study how ...