The studies indicated comparable growth trends regardless of whether therapy was initiated before or after age 5. Vosoritide, a once-daily injectable therapy, may improve growth outcomes in children ...

RPL30 showed the highest fold-change difference in patients with PBC compared to healthy people. Anti-RPL30 seems to be a promising biomarker for the diagnosis of primary biliary cholangitis (PBC) ...

The prognostic model for NMOSD-optic neuritis risk score included female gender, optic neuritis in both eyes, the absence of pain, and chiasmal involvement detected in orbital magnetic resonance ...

Impairments in memory recall and verbal fluency were especially pronounced, while global cognitive function was mildly affected in patients with NMOSD. Cognitive impairments are common in patients ...

Using a cutoff value of 1.87 µmol/L, CuEXC achieved a sensitivity of 76.9% and a specificity of 99.6% in differentiating newly diagnosed WD from non-Wilsonian hepatic disease. Relative exchangeable ...

The proportion of CD38+HLA-DR+CD8+ T cells was significantly higher in the blood of patients with cirrhosis compared to healthy controls. They also showed that the ratio of these cells was strongly ...

Treatment with inebilizumab led to higher rates of flare-free, treatment-free remission and a significant reduction in steroid use. Inebilizumab, a CD19-targeting monoclonal antibody, significantly ...

In this study, about half of the patients with malignant lymphoma exhibited markedly elevated IgG4-RD levels, which raises the possibility of misdiagnosis as IgG4-RD. Patients with immunoglobulin ...

Patients with ARFID symptoms experienced higher gastrointestinal symptom burden and worse health-related quality of life. Nearly half of patients with systemic sclerosis (SSc) screened positive for ...

Knowing the performance of core needle biopsy by subtype helps guide biopsy selection and may reduce procedural risk and cost. Core needle biopsy (CNB) is highly sensitive for diagnosing diffuse large ...

Never smoking and being physically active reduced all-cause mortality in patients with psoriatic diseases. An ideal lifestyle—defined as never smoking, maintaining a body mass index (BMI) under 25, ...

A patient with severe, treatment-resistant GPP and an IL36RN mutation showed rapid and sustained improvement after a single 900 mg dose of spesolimab. Spesolimab has shown potential in managing acute ...