Protein aggregation can occur due to a variety of causes. There are four classes that these causes can be categorized into, which are detailed below. Mutations that occur in the DNA …

Jul 1, 2023 · Protein aggregation studies are important to understand the mechanism behind the occurrence of various protein misfolding and aggregation diseases. Protein aggregation can …

Jan 9, 2026 · Protein aggregation is the process by which misfolded proteins adopt a conformation that cause its polymerization into aggregates and organized fibrils.

An understanding of protein aggregation in vitro is critical to the success of these efforts. The deliberate design of self‐assembling (aggregating) peptides and proteins to form bio‐inspired …

Jul 8, 2025 · Protein aggregation refers to the spontaneous association of proteins into larger, nonnative structures, leading to the formation of aggregates with distinct physicochemical …

Jul 31, 2025 · Protein aggregation occurs when unfolded or partially folded protein molecules interact with each other, forming clusters or larger complexes. This process can be triggered …

Nov 7, 2025 · Protein aggregation is a critical phenomenon that occurs when certain proteins, rather than folding into a single, unique native conformation, adopt alternative, often misfolded …

Protein aggregates represent an energetically stable, but non-functional alternative to the normal, functional, and soluble state of most proteins. In the context of human disease, aggregation …

The aggregation process involves several protein-protein interactions, such as hydrophobic and electrostatic interactions, which are concentration-dependent; an increase in protein …

To provide guidance on how to analyse protein aggregation, in this review we summarize the most commonly investigated aspects of protein aggregation with some popular corresponding …