Speedball (drug) - Wikipedia
Speedball, powerball, or over and under[1] is the polydrug mixture of a stimulant with a depressant, usually an opioid. The most well-known mixture used for recreational drug use is …
Speedball (Heroin & Cocaine) Abuse And Recovery
5 days ago · A speedball is a dangerous mix of a stimulant (most often cocaine) and a depressant (most often heroin or another opioid). This combination is especially risky because the …
Speedballing - Effects, Overdose Risk & Treatment Options
Oct 19, 2025 · A speedball is a dangerous combination of a stimulant drug, such as cocaine, and a depressant drug, most commonly heroin. The two drugs have opposite effects on the body, …
Understanding Speedball Drug: Effects, Risks, and Treatment
A speedball is a combination of heroin and cocaine that is usually injected, snorted or smoked. The high produced by the stimulant effect of cocaine combined with the depressant effect of …
Speedball Use: Overdose Risks, Effects, and Harm Reduction
Mar 14, 2025 · A speedball is a combination of a stimulant (usually cocaine or methamphetamine) and a CNS depressant (typically an opioid), used simultaneously to produce an intense and …
Speedball Drugs: Effects, Risks, and Overdose Signs
Dec 2, 2025 · A “speedball” refers to combining two substances with opposing effects: a stimulant and a depressant. The classic mixture involves cocaine, a central nervous system (CNS) …
What Is a Speedball? - Recovery.com
Sep 10, 2025 · A speedball is a combination of 2 strong and potentially lethal substances: heroin and cocaine. This deadly mix of uppers and downers is often prepared by mixing powdered …