What is Alpha-1? Learn More Here
What is Alpha-1? Learn More Here
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Alpha-1 antitrypsin (A1AT) is a protein that prevents various enzymes like neutrophil elastase from breaking down elastin in the lungs. Sometimes a mutation is present in the SERPINA1 gene, resulting in Alpha-1 antitrypsin deficiency (A1AD). When this happens the lungs lose a significant portion of their elasticity, leading to respiratory complications like chronic obstructive pulmonary disease. To learn more about #A1AD, watch our video: osms.it/alpha120d2 #FOAMed #learnmedicine #Osmosis #board
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3K views · 70 reactions | Liver disease associated with mutant alpha1-antitrypsin results from accumulation of mutant Z-AAT in hepatocytes. Can fazirsiran, an RNA interference therapeutic, reduce liver Z-AAT levels? New research findings are summarized in a short video. https://nej.md/3vKaYzw | The New England Journal of Medicine | Facebook
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